Research

Mixed

Strict avoidance of trans-fats, hydrogenated/oxidized fats, adulterated oils, emulsifiers, glutamatergic flavor enhancers, and non-sugar sweeteners significantly improves blood pressure control and reduces antihypertensive drug requirements in patients with essential hypertension.

To improve blood pressure and reduce medication needs, focus on eliminating specific 'toxic' dietary components rather than just counting calories. Strictly avoid trans-fats, hydrogenated oils, and heavily processed oils. Be cautious with artificial sweeteners and flavor enhancers (like MSG); try eliminating them for a few weeks to see if your blood pressure improves, then reintroduce them one by one to check for personal intolerance. Prioritize cold-pressed, unheated oils and whole foods. This approach works best when combined with your current blood pressure medications until your doctor advises otherwise.

LimitedSupportsLOW confidence
The dietary intervention emphasises the need to carefully differentiate between harmful and beneficial oils and fats. Trans-fats, hydrogenated / oxidised fats, adulterated oils, emulsifiers should be strictly avoided... Glutamatergic flavour enhancers and non-sugar (aspartatergic) sweeteners should also be avoided... Using data at baseline and from all available timepoints after dietary intervention, two-way ANOVA confirmed highly significant improvement of BP control (P < 0.0001) and reduction of ADTR score (P = 0.0008) in GOOD compliers.
CP Chijioke et al. · Nigerian Journal of Clinical Practice · 2024

Why this rating

Small sample size (n=7-9), open trial design, retrospective controls, and lack of randomization limit generalizability.

Source

Personalized Food Avoidance Dietary Approach for Psoriasis and Hypertension: A Case Study and Pilot Trial

CP Chijioke et al. · Nigerian Journal of Clinical Practice · 2024

DOI 10.4103/njcp.njcp_152_24

case_series · n=9Cited 1×
Read the paper
DOI resolved against Crossref · corpus check 2026-06-10

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