Mixed

Pre-exhaustion resistance training (single-joint immediately before multi-joint) does not produce superior muscle hypertrophy or strength gains compared to traditional resistance training and may result in slightly lower hypertrophy due to reduced volume load.

If your goal is maximum muscle growth, stick to traditional resistance training (performing all sets of one exercise before moving to the next). While pre-exhaustion (doing a single-joint exercise right before a compound one) is time-efficient and viable for strength and endurance, it likely results in slightly less muscle growth because you lift less total weight (volume load) on the compound movements due to fatigue. Do not sacrifice volume load on compound lifts for the sake of pre-fatiguing muscles if hypertrophy is your primary goal.