Research

Mixed

Consumption of sugar-sweetened beverages (SSBs) is causally associated with a significant global burden of incident type 2 diabetes (T2D) and cardiovascular disease (CVD), mediated by both direct metabolic effects and adiposity.

Reduce or eliminate sugar-sweetened beverages to significantly lower your risk of developing type 2 diabetes and cardiovascular disease. The risk is not just from weight gain but from how sugar is metabolized directly. This is especially critical if you are young, male, or live in urban areas in high-burden regions like Latin America or Sub-Saharan Africa.

StrongSupportsHIGH confidence
Sugar-sweetened beverages (SSBs) contribute to excess weight gain and cardiometabolic diseases such as type 2 diabetes (T2D) and cardiovascular disease (CVD), both directly and mediated by weight gain.
Laura Lara-Castor et al. · Nature Medicine · 2025

Why this rating

The study uses a Comparative Risk Assessment framework based on independent lines of evidence including meta-analyses of prospective cohorts and randomized controlled trials across 184 countries.

Source

Burdens of type 2 diabetes and cardiovascular disease attributable to sugar-sweetened beverages in 184 countries

Laura Lara-Castor et al. · Nature Medicine · 2025

cohort · n=2900000Cited 83×
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