Research
Energy balance
The overall mean weight reduction from week 0 to 88 was 25.3% for tirzepatide and 9.9% for placebo.
Tirzepatide leads to significantly greater weight loss compared to placebo over the study period.
StrongSupportsmedium confidence
The overall mean weight reduction from week 0 to 88 was 25.3% for tirzepatide and 9.9% for placebo.
Why this rating
Based on study design from abstract.
Source
Continued Treatment With Tirzepatide for Maintenance of Weight Reduction in Adults With Obesity
Louis J. Aronne et al. · JAMA · 2023
rct · n=783Cited 679×
Read the paper This is one finding among thousands. Every one is graded and traced to its source, so you can see what the evidence actually supports. Browse the research →