Research
Energy balance
VLCD and COMB resulted in a 5.4 and 7 percentage-point greater weight loss than SEM, respectively.
Practitioners should consider VLCD or its combination with Semaglutide for greater weight loss in patients with T2D.
StrongSupportsmedium confidence
VLCD and COMB resulted in a 5.4 and 7 percentage-point greater weight loss than SEM, respectively.
Why this rating
Based on the randomized controlled trial design mentioned in the abstract.
Source
Metabolic effects of very-low calorie diet, Semaglutide, or combination of the two, in individuals with type 2 diabetes mellitus
Oluwaseun Anyiam et al. · Clinical Nutrition · 2024
DOI 10.1016/j.clnu.2024.06.034
otherCited 31×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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