Research
Energy balance
Tirzepatide (TZP) resulted in a mean body weight loss of 16.7 kg compared to 8.3 kg with placebo (PBO) after 18 weeks (p<0.001).
Tirzepatide may be an effective treatment for weight loss in individuals with obesity.
StrongSupportsmedium confidence
At 18wk, mean body weight loss was 16.7 kg with TZP and 8.3 kg with PBO (p<0.001).
Why this rating
Based on a randomized blinded clinical trial design.
Source
128-OR: The Effect of Tirzepatide during Weight Loss on Food Intake, Appetite, Food Preference, and Food Craving in People with Obesity
CORBY K. MARTIN et al. · Diabetes · 2023
DOI 10.2337/db23-128-or
rct · n=55Cited 20×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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