Research
Metabolic adaptation
CagrANDsema also reduced glycosylated hemoglobin (HbA1c) by -0.33% compared to placebo.
CagrANDsema may help improve glycemic control in obese individuals.
StrongSupportsmedium confidence
cagrANDsema reduced HbA1c by - 0.33% (95% CI: -0.41, -0.25).
Why this rating
Based on a systematic review and meta-analysis of RCTs.
Source
Efficacy and safety of GLP-1RAs for people with obesity: A systematic review based on RCT and Bayesian network meta-analysis
Hong Li et al. · Biomedicine & Pharmacotherapy · 2024
DOI 10.1016/j.biopha.2024.116150
Meta-analysisCited 26×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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