Research
Hormonal
High-dose once-weekly semaglutide can significantly reduce weight.
Clinicians can consider high-dose semaglutide as an effective option for weight management.
StrongSupportsmedium confidence
High-dose once-weekly semaglutide can significantly reduce weight.
Why this rating
Based on four phase 3, multicenter, randomized, double-blind trials.
Source
High-Dose Once-Weekly Semaglutide: A New Option for Obesity Management
Courtney L. Bradley et al. · Annals of Pharmacotherapy · 2021
DOI 10.1177/10600280211053867
reviewCited 13×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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