Research
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At 5-6 months, the mean weight reduction was 7.9%, with 56% of participants achieving more than 5% weight loss.
Phentermine/topiramate ER can be effective for weight loss in obese patients.
StrongSupportsmedium confidence
At 5-6 months, the mean weight reduction was 7.9%, with sex-specific losses of 7.1% in men and 8.2% in women. Over 56% of participants achieved more than 5% weight loss.
Why this rating
Based on the multicenter study design with a large cohort.
Source
Efficacy of phentermine/topiramate extended release in weight management and metabolic profiles: A multicentre study in South Korea
Kyoung Min Kim et al. · Diabetes Obesity and Metabolism · 2025
DOI 10.1111/dom.16342
cohort · n=1839Cited 1×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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