Research
Energy balance
Cagrisema produced significantly greater percentage weight loss than semaglutide with a mean difference of -7.47% (95% CI: -10.58, -4.36; p < 0.001).
Cagrisema may be a more effective option for weight loss in obese patients compared to semaglutide.
StrongSupportsmedium confidence
Cagrisema produced significantly greater percentage [MD -7.47% (95% CI: -10.58, -4.36); p < 0.001] weight loss than semaglutide.
Why this rating
Based on a systematic review and meta-analysis of randomized controlled trials.
Source
Efficacy and Safety of Cagrilintide and Cagrisema Versus Semaglutide as Anti‐Obesity Medications: A Systematic Review, Meta‐Analysis and Meta‐Regression
Muhammad Ahmed et al. · Diabetes Obesity and Metabolism · 2026
Meta-analysis
Read the paper This is one finding among thousands. Every one is graded and traced to its source, so you can see what the evidence actually supports. Browse the research →