Research

Mixed

High body mass index (BMI) is a significant contributor to premature cardiometabolic mortality, particularly in adults aged 45-69, largely mediated through its effects on blood pressure and glucose.

Maintaining a healthy weight is crucial for preventing early death from heart disease or diabetes, especially if you are middle-aged. This risk is often linked to blood pressure and blood sugar levels, so managing weight helps manage those metrics.

GoodSupportsHIGH confidence
High body-mass index (BMI) (42,643 deaths; 95%UI: 40,161 to 45,111)... The relative greater impact of high BMI on premature mortality was mostly due to suboptimal BMI among adults between 45 and 69 years of age.
Marcia C. de Oliveira Otto et al. · PLoS ONE · 2016

Why this rating

Based on GBD data and meta-analyses.

Source

The Impact of Dietary and Metabolic Risk Factors on Cardiovascular Diseases and Type 2 Diabetes Mortality in Brazil

Marcia C. de Oliveira Otto et al. · PLoS ONE · 2016

cohort · n=34003Cited 73×
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