Metabolic adaptation

Low birth weight (< 5.5 lb) is associated with an increased risk of hypertension (age-adjusted odds ratio of 1.26) and diabetes mellitus (age-adjusted odds ratio of 1.75).

Practitioners should consider birth weight as a potential risk factor for hypertension and diabetes in adult patients.

StrongSupportsmedium confidence

Compared with men in the referent birth weight category (7.0 to 8.4 lb), men who weighed < 5.5 lb had an age-adjusted odds ratio for hypertension of 1.26 (95% confidence interval [CI], 1.11 to 1.44) and for diabetes mellitus of 1.75 (95% CI, 1.21 to 2.54).

Gary C. Curhan et al. · Circulation · 1996

Why this rating

Based on a large cohort study design.

Source

Birth Weight and Adult Hypertension, Diabetes Mellitus, and Obesity in US Men

Gary C. Curhan et al. · Circulation · 1996

cohort · n=22846Cited 924×

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