Mixed
Achieving remission from type 2 diabetes through lifestyle intervention significantly reduces the long-term incidence of chronic kidney disease and cardiovascular disease compared to maintaining active diabetes.
Achieving remission from type 2 diabetes through intensive lifestyle changes—specifically significant weight loss, improved diet, and increased physical activity—substantially lowers your risk of developing kidney disease and heart problems over the long term. You do not need to maintain remission forever to gain these benefits; even short periods of remission are associated with significantly better health outcomes compared to staying in active diabetes.
Participants with type 2 diabetes with evidence of remission had a substantially lower incidence of CKD and CVD, respectively, compared with participants who did not achieve remission.
Why this rating
Post-hoc analysis of a large, long-term RCT (Look AHEAD) with robust statistical adjustment, though observational nature of the remission classification limits causal inference.
Source
Impact of remission from type 2 diabetes on long-term health outcomes: findings from the Look AHEAD study
Edward W. Gregg et al. · Diabetologia · 2024
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