Research
Metabolic adaptation
Bariatric surgery was associated with a lower incidence of major adverse cardiovascular events (MACE) in patients with cardiovascular disease and obesity, with an adjusted hazard ratio of 0.58.
Bariatric surgery may significantly reduce the risk of serious cardiovascular events in obese patients with heart disease.
StrongSupportsmedium confidence
The primary outcome occurred in 11.5% (151/1319) of the surgery group and 19.6% (259/1319) of the controls (adjusted hazard ratio [HR], 0.58 [95% CI, 0.48–0.71]; P <0.001).
Why this rating
The study is a propensity score–matched cohort study, indicating a strong design.
Source
Bariatric Surgery and Cardiovascular Outcomes in Patients With Obesity and Cardiovascular Disease:
Aristithes G. Doumouras et al. · Circulation · 2021
cohort · n=2638Cited 197×
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