Research
Metabolic adaptation
Low-carbohydrate diets are associated with a 50% higher risk of cardiovascular disease mortality.
Health professionals should consider the cardiovascular risks associated with low-carbohydrate diets.
GoodSupportsmedium confidence
Participants with the lowest carbohydrates intake (quartile 4 of LCD) had the highest risk of cardiovascular disease (CVD) (50%) mortality.
Why this rating
Based on the analysis of a large cohort study.
Source
Lower carbohydrate diets and all-cause and cause-specific mortality: a population-based cohort study and pooling of prospective studies
Mohsen Mazidi et al. · European Heart Journal · 2019
DOI 10.1093/eurheartj/ehz174
Meta-analysisCited 152×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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- Participants with the lowest carbohydrate intake (quartile 4 of LCD) had a 32% higher risk of overall mortality compared to the highest quartile (Q1).Good
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