Research
Hormonal
Insulin infusions without amino acids resulted in a progressive decrement in leucine Ra (14 to 45%), NORd (16-41%), and OXRd (3-56%) compared with basal values.
Insulin alone can significantly reduce protein breakdown, but the presence of amino acids enhances this effect.
StrongSupportsmedium confidence
INS infusions without AA resulted in a progressive decrement in LEU Ra (14 to 45%), NORd (16-41%), and OXRd (3-56%) compared with basal values.
Why this rating
Based on study design from abstract.
Source
Amino acids augment insulin's suppression of whole body proteolysis
Paul J. Flakoll et al. · American Journal of Physiology-Endocrinology and Metabolism · 1989
DOI 10.1152/ajpendo.1989.257.6.e839
otherCited 148×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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