Research
Metabolic adaptation
Change in apnea–hypopnea index (AHI) over time was related to amount of weight loss, baseline AHI, and intervention independent of weight change.
Understanding these relationships can help tailor interventions for better OSA management.
StrongSupportsmedium confidence
Change in AHI over time was related to amount of weight loss, baseline AHI, visit year (P values < 0.0001), and intervention independent of weight change (P = 0.01).
Why this rating
Based on the large randomized controlled trial design.
Source
Effects of Weight Loss on Obstructive Sleep Apnea Severity. Ten-Year Results of the Sleep AHEAD Study
Samuel T. Kuna et al. · American Journal of Respiratory and Critical Care Medicine · 2020
cohort · n=134Cited 138×
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