Research
Metabolic adaptation
Metformin reduced weight by 2.9% and BMI by 2.9% in men.
Metformin can be effective in reducing weight and BMI in men at risk for diabetes.
StrongSupportsmedium confidence
Metformin reduced weight (-2.9%) and BMI (-2.9%) in men.
Why this rating
Based on the randomized controlled trial design of the Diabetes Prevention Program.
Source
Body Size and Shape Changes and the Risk of Diabetes in the Diabetes Prevention Program
Wilfred Y. Fujimoto et al. · Diabetes · 2007
DOI 10.2337/db07-0009
rct · n=758Cited 116×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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