Research
Energy balance
The mean effect of individualized lifestyle interventions for weight reduction in people with SMI is statistically significant but clinically insignificant.
Practitioners should be aware that while interventions may show statistical benefits, the practical impact on weight may be limited.
StrongQualifiesmedium confidence
There is a statistically significant, but clinically insignificant, mean effect of individualized lifestyle interventions for weight reduction in people with SMI.
Why this rating
Based on meta-analysis of randomized clinical trials.
Source
Lifestyle Interventions for Weight Management in People with Serious Mental Illness: A Systematic Review with Meta-Analysis, Trial Sequential Analysis, and Meta-Regression Analysis Exploring the Mediators and Moderators of Treatment Effects
Helene Speyer et al. · Psychotherapy and Psychosomatics · 2019
DOI 10.1159/000502293
Meta-analysisCited 115×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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