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Significant disproportionality for semaglutide remained in patients with coreported use of antidepressants and benzodiazepines.
Clinicians should consider the interaction of semaglutide with antidepressants and benzodiazepines when assessing risk.
StrongSupportsmedium confidence
which remained significant in patients with coreported use of antidepressants (ROR, 4.45; 95% CI, 2.52-7.86; IC, 1.96; 95% CI, 0.98-2.63) and benzodiazepines (ROR, 4.07; 95% CI, 1.69-9.82; IC, 1.67; 95% CI, 0.11-2.65).
Why this rating
Based on the analysis of WHO data.
Source
Disproportionality Analysis From World Health Organization Data on Semaglutide, Liraglutide, and Suicidality
Georgios Schoretsanitis et al. · JAMA Network Open · 2024
DOI 10.1001/jamanetworkopen.2024.23385
other · n=269Cited 86×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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