Research
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Once-weekly cagrilintide-semaglutide (at a dose of 2.4 mg each) resulted in a significantly lower body weight than placebo in adults with obesity and type 2 diabetes.
Practitioners can consider cagrilintide-semaglutide as an effective treatment for weight management in this population.
StrongSupportsmedium confidence
Once-weekly cagrilintide-semaglutide (at a dose of 2.4 mg each) resulted in a significantly lower body weight than placebo in adults with obesity and type 2 diabetes.
Why this rating
Based on the phase 3a, double-blind, randomized, placebo-controlled trial design.
Source
Cagrilintide–Semaglutide in Adults with Overweight or Obesity and Type 2 Diabetes
Melanie J. Davies et al. · New England Journal of Medicine · 2025
DOI 10.1056/nejmoa2502082
rct · n=1206Cited 78×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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