Research
Energy balance
The highest achieved tertiles of EPA and DHA were associated with neither benefit nor harm in patients at high cardiovascular risk.
Practitioners should note that increasing EPA and DHA levels may not provide cardiovascular benefits in high-risk patients.
StrongRefutesmedium confidence
Among patients treated with ω-3 CA, the highest achieved tertiles of EPA and DHA were associated with neither benefit nor harm in patients at high cardiovascular risk.
Why this rating
Based on study design from abstract.
Source
Association Between Achieved ω-3 Fatty Acid Levels and Major Adverse Cardiovascular Outcomes in Patients With High Cardiovascular Risk
Steven E. Nissen et al. · JAMA Cardiology · 2021
DOI 10.1001/jamacardio.2021.1157
rct · n=13078Cited 75×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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