Research
Hormonal
Acute elevations of plasma glucose to two times basal levels result in a marked stimulation of whole body proteolysis during hyperinsulinemia.
Practitioners should be aware that elevated glucose levels can significantly increase proteolysis in the context of hyperinsulinemia.
StrongSupportsmedium confidence
The present study demonstrates that, during hyperinsulinemia, acute elevations of plasma glucose to two times basal levels result in a marked stimulation of whole body proteolysis during hyperinsulinemia.
Why this rating
Based on study design from abstract.
Source
Acute hyperglycemia enhances proteolysis in normal man
Paul J. Flakoll et al. · American Journal of Physiology-Endocrinology and Metabolism · 1993
DOI 10.1152/ajpendo.1993.265.5.e715
otherCited 71×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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