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Cellular
The endogenous rate of leucine appearance dropped by 80% from basal during period I and by 44% during period II.
This indicates that acute hyperglycemia can significantly affect protein metabolism.
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The endogenous rate of leucine appearance (index of proteolysis in mumol.kg-1 x h-1) dropped by 80% from basal during period I (P < 0.01) but only by 44% during period II.
Why this rating
Based on study design from abstract.
Source
Acute hyperglycemia enhances proteolysis in normal man
Paul J. Flakoll et al. · American Journal of Physiology-Endocrinology and Metabolism · 1993
DOI 10.1152/ajpendo.1993.265.5.e715
otherCited 71×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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