Research
Metabolic adaptation
Increased fatty acid availability does not systematically improve exercise capacity despite substantial muscle glycogen sparing (15-48% compared with control).
Increased fat availability may not enhance performance, even with reduced glycogen use.
StrongRefutesmedium confidence
Despite substantial muscle glycogen sparing (15-48% compared with control), exercise capacity is not systematically improved in the face of increased FA availability.
Why this rating
The findings are based on studies involving both untrained and well-trained subjects.
Source
Effect of increased fat availability on metabolism and exercise capacity
John A. Hawley · Medicine & Science in Sports & Exercise · 2002
DOI 10.1097/00005768-200209000-00014
otherCited 66×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
More from this paper
- Ingestion of long-chain triglyceride (LCT) solutions or infusion of intralipid before exercise leads to significant reductions in whole-body carbohydrate oxidation and decreased muscle glycogen utilization during moderate and intense dynamic exercise lasting 15-60 min.Strong
- The effects of increased fatty acid provision on rates of muscle glucose uptake during exercise are equivocal.Strong
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