Research
Molecular
Caloric restriction can stimulate mitochondrial biogenesis and improve mitochondrial efficiency.
Implementing caloric restriction may enhance mitochondrial function and combat insulin resistance.
StrongSupportsmedium confidence
Caloric restriction and the adiponectin signaling pathway, however, can stimulate mitochondrial biogenesis by elevating the transcriptional machinery that regulates mitochondrial mass.
Why this rating
The findings are based on recent research highlighted in the review.
Source
Diet, energy metabolism and mitochondrial biogenesis
Anthony E. Civitarese et al. · Current Opinion in Clinical Nutrition & Metabolic Care · 2007
DOI 10.1097/mco.0b013e3282f0ecd2
reviewCited 51×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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