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GLP-1 receptor agonist use was not associated with an increased risk of pulmonary aspiration compared to SGLT-2 inhibitor use.
Practitioners can consider GLP-1 receptor agonists safe regarding pulmonary aspiration risk before endoscopy.
StrongRefutesmedium confidence
Compared with SGLT-2 inhibitor use, GLP-1 receptor agonist use was not associated with an increased risk of pulmonary aspiration (pooled risk ratio 0.98, 95% CI 0.73 to 1.31).
Why this rating
Based on the cohort study design.
Source
Glucagon-like peptide-1 receptor agonists before upper gastrointestinal endoscopy and risk of pulmonary aspiration or discontinuation of procedure: cohort study
Wajd Alkabbani et al. · BMJ · 2024
DOI 10.1136/bmj-2024-080340
cohort · n=43365Cited 51×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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