Research
Metabolic adaptation
There were no significant changes in HbA1c between year 1 and year 4 for all bMVPA timing groups.
Practitioners should be aware that initial improvements in glycemic control may not persist long-term.
StrongRefutesmedium confidence
For all the year-4 bMVPA timing groups, there were no significant changes in HbA1c between year 1 and 4.
Why this rating
Based on study design from abstract.
Source
Association of Timing of Moderate-to-Vigorous Physical Activity With Changes in Glycemic Control Over 4 Years in Adults With Type 2 Diabetes From the Look AHEAD Trial
Jingyi Qian et al. · Diabetes Care · 2023
DOI 10.2337/dc22-2413
cohort · n=2416Cited 50×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
More from this paper
- bMVPA performed in the afternoon is associated with a greater reduction in HbA1c compared to inactive individuals, with a reduction of -0.22%.Strong
- The odds of discontinuation of glucose-lowering medications at year 1 differed by bMVPA timing, with the afternoon group having the highest odds (odds ratio 2.13).Strong
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