Research
Metabolic adaptation
The risk of MACE decreases after approximately 20% of weight loss in nonsurgical patients.
Practitioners should aim for at least 20% weight loss in nonsurgical patients to reduce cardiovascular risk.
StrongSupportsmedium confidence
the risk of MACE decreases after approximately 20% in the nonsurgical group.
Why this rating
Based on a large matched-cohort study design.
Source
How Much Weight Loss is Required for Cardiovascular Benefits? Insights From a Metabolic Surgery Matched-cohort Study
Ali Aminian et al. · Annals of Surgery · 2020
DOI 10.1097/sla.0000000000004369
cohort · n=7201Cited 49×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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