Research
Hormonal
Mexican Pima Indians had lower absolute leptin concentrations than U.S. Pima Indians, but higher after adjustment for percent body fat, waist circumference, age, and sex.
Understanding the influence of lifestyle and environment on leptin can guide dietary and activity recommendations.
StrongQualifiesmedium confidence
Among nondiabetic subjects, Mexican Pima Indians had lower absolute leptin concentrations than U.S. Pima Indians, but higher after adjustment for percent body fat, waist circumference, age, and sex.
Why this rating
The claim is based on comparative analysis with statistical adjustments.
Source
Plasma leptin concentrations in Pima Indians living in drastically different environments.
Caroline S. Fox et al. · Diabetes Care · 1999
DOI 10.2337/diacare.22.3.413
cross-sectional · n=642Cited 47×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
More from this paper
- Leptin concentration is strongly correlated with percent fat in both Mexican and U.S. Pima Indians (r = 0.83 and r = 0.86, respectively, P < 0.0001).Strong
- Among U.S. Pima Indians, subjects with type 2 diabetes had lower leptin than nondiabetic subjects (difference = 6.9 +/- 1.0 ng/ml, P < 0.002).Strong
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