Research
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The proportion of new users of semaglutide (Ozempic ® ) with a record of type 2 diabetes (T2D) declined from 99% in 2018 to only 67% in 2022, before increasing again to 87% in 2023.
Practitioners should note the changing demographics of semaglutide users, indicating a shift towards off-label use.
ModerateSupportsmedium confidence
The proportion of semaglutide (Ozempic ® ) new users who had a record of T2D declined from 99% in 2018 to only 67% in 2022, increasing again to 87% in 2023.
Why this rating
Based on a cross-sectional study design.
Source
Semaglutide (Ozempic®) Use in Denmark 2018 Through 2023 ‒ User Trends and off-Label Prescribing for Weight Loss
Aurélie Mailhac et al. · Clinical Epidemiology · 2024
DOI 10.2147/clep.s456170
cross-sectional · n=91626Cited 47×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
More from this paper
- The new user rate of semaglutide (Ozempic ® ) remained stable at approximately 4 per 1000 adult person-years between 2019 and 2021 and then peaked at 10 per 1000 in the first quarter of 2023.Moderate
- Most initiators of semaglutide (Ozempic ® ) with T2D had suboptimal glucose control, with 83% having an HbA1c ≥ 48 mmol/mol.Moderate
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