Research
Energy balance
The cost needed to treat per 1% of body weight reduction with tirzepatide is estimated at $985 compared with $1845 with semaglutide.
Tirzepatide is more cost-effective for achieving weight loss in this population.
StrongSupportsmedium confidence
Accordingly, the cost needed to treat per 1% of body weight reduction with tirzepatide is estimated at $985 (95% CI: $908-$1075) compared with $1845 (95% CI: $1707-$1989) with semaglutide.
Why this rating
Based on cost analysis derived from treatment outcomes.
Source
Tirzepatide versus semaglutide for weight loss in patients with type 2 diabetes mellitus: A value for money analysis
Joseph Azuri et al. · Diabetes Obesity and Metabolism · 2022
DOI 10.1111/dom.14940
otherCited 41×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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