Research
Metabolic adaptation
GLP-1 RA therapy is associated with significant reductions in procedural interventions (RR, 0.44; 95% CI, 0.30-0.63; P < .001).
GLP-1 RAs may reduce the need for surgical or other procedural interventions in IIH management.
StrongSupportsmedium confidence
Procedures (RR, 0.44; 95% CI, 0.30-0.63; P < .001) were lower in the GLP-1 RA group.
Why this rating
Based on the large retrospective cohort study design.
Source
GLP-1 Receptor Agonists in Idiopathic Intracranial Hypertension
Georgios S. Sioutas et al. · JAMA Neurology · 2025
cohort · n=44373Cited 35×
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