Research
Energy balance
Beneficial effects of replacing saturated fat with polyunsaturated or monounsaturated fat or carbohydrates remain elusive.
Dietary recommendations should be cautious about promoting replacements for SFA without clear evidence of benefit.
StrongQualifiesmedium confidence
Beneficial effects of replacement of SFA by polyunsaturated or monounsaturated fat or carbohydrates remain elusive.
Why this rating
Based on the review of multiple study designs including RCTs and meta-analyses.
Source
Saturated fat: villain and bogeyman in the development of cardiovascular disease?
Reimara Valk et al. · European Journal of Preventive Cardiology · 2022
DOI 10.1093/eurjpc/zwac194
Meta-analysisCited 33×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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