Research
Energy balance
Replacing 5% energy from animal fat with 5% energy from plant fat is associated with a 4% to 24% reduction in overall mortality and a 5% to 30% reduction in CVD mortality.
Encouraging dietary fat substitution can significantly reduce mortality risks.
StrongSupportsmedium confidence
Replacement of 5% energy from animal fat with 5% energy from plant fat ... was associated with a lower risk for mortality: 4% to 24% reduction in overall mortality, and 5% to 30% reduction in CVD mortality.
Why this rating
Based on a large prospective cohort study.
Source
Plant and Animal Fat Intake and Overall and Cardiovascular Disease Mortality
Bin Zhao et al. · JAMA Internal Medicine · 2024
DOI 10.1001/jamainternmed.2024.3799
cohort · n=407531Cited 31×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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- A greater intake of plant fat is associated with a lower risk for overall mortality (HRs, 0.91) and cardiovascular disease (CVD) mortality (HRs, 0.86), particularly from grains and vegetable oils.Strong
- A higher intake of total animal fat is associated with an increased risk for overall mortality (HRs, 1.16) and CVD mortality (HRs, 1.14).Strong
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