Research
Macro partitioning
Flavonoids inhibit glucose transporters (GLUT2, GLUT5, GLUT7), thereby reducing intestinal glucose and fructose absorption.
Eating flavonoid-rich foods might slightly slow down sugar absorption by affecting transporters in the gut. This is a subtle effect and should not replace a balanced diet, but it may offer some metabolic benefit.
ModerateSupportsMEDIUM confidence
Flavonoids such as tiliroside, myricetin, phloretin, EGCG, and apigenin were reported to inactivate GLUT2 (60, 61). Quercetin inhibits glucose and fructose transport by GLUT2, binding to a non-sugar binding site.
Why this rating
Based on in vitro studies and molecular docking; human clinical data for specific flavonoid dosages is not provided.
Source
Role of flavonoids in controlling obesity: molecular targets and mechanisms
Anns Mahboob et al. · Frontiers in Nutrition · 2023
DOI 10.3389/fnut.2023.1177897
narrative_reviewCited 43×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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