Research
Metabolic adaptation
Fatty acid metabolism is a key pathway modified by weight loss that predicts body weight maintenance 18 months after intended weight loss.
Practitioners should consider the role of fatty acid metabolism in developing weight maintenance strategies.
StrongSupportsmedium confidence
Unbiased RNA sequencing of adipose and skeletal muscle biopsies revealed fatty acid metabolism as a key pathway modified by weight loss.
Why this rating
Based on the analysis of a randomized trial with a significant sample size.
Source
An Integrated Understanding of the Molecular Mechanisms of How Adipose Tissue Metabolism Affects Long-term Body Weight Maintenance
Knut Mai et al. · Diabetes · 2018
cohort · n=143Cited 30×
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