Research
Metabolic adaptation
Weight loss elicits physiological adaptations that oppose ongoing weight loss.
Practitioners should consider physiological adaptations when advising clients on weight maintenance.
StrongSupportsmedium confidence
a second, perhaps more fundamental, explanation is that weight loss elicits physiological adaptations — principally an increase in hunger and a decrease in resting energy expenditure.
Why this rating
The claim is based on established physiological responses to weight loss.
Source
Weight-Loss Maintenance — Mind over Matter?
David S. Ludwig et al. · New England Journal of Medicine · 2010
DOI 10.1056/nejme1011361
reviewCited 26×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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