Research
Metabolic adaptation
Aging may impair the ability to maintain normal blood glucose homeostasis following large meals.
Understanding this impairment can guide dietary interventions for older adults to better manage blood glucose levels.
StrongSupportsmedium confidence
We tested the hypothesis that aging is associated with an impairment in the ability to maintain normal blood glucose homeostasis following the consumption of large meals but not small ones.
Why this rating
The study design involved controlled meal consumption and serial blood sampling.
Source
Blood Glucose and Hormonal Responses to Small and Large Meals in Healthy Young and Older Women
Kathleen J. Melanson et al. · The Journals of Gerontology Series A · 1998
DOI 10.1093/gerona/53a.4.b299
other · n=16Cited 28×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
More from this paper
- Older women show exaggerated hormonal and metabolite responses and a delayed return to premeal values following consumption of large meals (2092 and 4184 kJ).Strong
- There is no significant difference in hormonal and metabolite responses between young and older women after fasting and consumption of a small meal (1046 kJ).Strong
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