Research
Molecular
Endurance-trained males (ETM) had higher [3H]-ouabain binding and 3-O-MFPase activity than recreationally active males (RAM) by 16%.
Endurance training enhances Na+,K+-pump activity compared to recreational activity.
StrongSupportsmedium confidence
[3H]-ouabain binding and 3-O-MFPase activity were each higher in ETM than in RAM, by 16% (P<0.03).
Why this rating
Based on the study design involving multiple groups and statistical significance.
Source
Effects of endurance training status and sex differences on Na<sup>+</sup>,K<sup>+</sup>‐pump mRNA expression, content and maximal activity in human skeletal muscle
Kate T. Murphy et al. · Acta Physiologica · 2007
DOI 10.1111/j.1748-1716.2006.01635.x
cross-sectional · n=65Cited 25×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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- Endurance-trained males (ETM) demonstrated lower alpha1, alpha3, beta2, and beta3 mRNA expression by 74%, 62%, 70%, and 82%, respectively, than recreationally active males (RAM).Strong
- Recreationally active males (RAM) demonstrated a 230% and 364% higher alpha3 and beta3 mRNA expression than recreationally active females (RAF), respectively.Strong
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