Research
Energy balance
GLP-1RAs have gastrointestinal side effects, particularly nausea, which limits their tolerability.
Clinicians should monitor for gastrointestinal side effects when prescribing GLP-1RAs.
StrongQualifiesmedium confidence
However, they have frequent gastrointestinal side effects, particularly nausea, which limits their tolerability.
Why this rating
The claim is based on expert opinion regarding side effects.
Source
Investigational glucagon-like peptide-1 agonists for the treatment of obesity
Brian Tomlinson et al. · Expert Opinion on Investigational Drugs · 2016
DOI 10.1080/13543784.2016.1221925
reviewCited 24×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
More from this paper
Related findings · Energy balance
- Achieving a total body weight loss of 10-15% (or >10-15 kg) through Total Diet Replacement (TDR) induces remission of Type 2 Diabetes in individuals with short-duration disease.Strong
- Bariatric surgery is superior to medical management alone for inducing significant long-term weight loss, remission of type 2 diabetes, and reduction in mortality for patients with BMI ≥ 40 or ≥ 35 with comorbidities.Strong
- Achieving type 2 diabetes remission requires significant weight loss (≥15 kg) via major caloric restriction, independent of macronutrient composition.Strong
This is one finding among thousands. Every one is graded and traced to its source, so you can see what the evidence actually supports. Browse the research →