Research
Metabolic adaptation
Retatrutide and orforglipron are effective in weight loss and improving metabolic parameters associated with obesity.
These drugs may be considered as therapeutic options for obesity management.
StrongSupportsmedium confidence
Recently published studies have shown that retatrutide, a triple-agonist of GLP-1, GIP, and glucagon receptor, and orforglipron, a GLP-1 receptor partial agonist, are effective in weight loss and improving various metabolic parameters associated with obesity.
Why this rating
The claim is based on recent studies as mentioned in the abstract.
Source
Gut hormones and appetite regulation
So‐hyeon Hong et al. · Current Opinion in Endocrinology Diabetes and Obesity · 2024
reviewCited 23×
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