Research
Energy balance
Semaglutide led to a weight reduction of 9.21 kg in the study population.
Semaglutide may assist in significant weight loss for patients in this demographic.
StrongSupportsmedium confidence
Semaglutide reduced body weight by 9.21 kg (95% CI, -11.68 to -6.75).
Why this rating
Based on the randomized clinical trial design.
Source
Semaglutide Treatment of Antipsychotic-Treated Patients With Schizophrenia, Prediabetes, and Obesity
Ashok Ainkaran Ganeshalingam et al. · JAMA Psychiatry · 2025
DOI 10.1001/jamapsychiatry.2025.2332
rct · n=154Cited 21×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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