Research
Metabolic adaptation
Increasing saturated fat intake was not associated with CVD or mortality and instead correlated with lower rates of diabetes, hypertension, and obesity.
Practitioners may reconsider the role of saturated fat in CVD risk and its potential benefits for metabolic health.
StrongRefutesmedium confidence
Increasing saturated fat intake was not associated with CVD or mortality and instead correlated with lower rates of diabetes, hypertension and obesity.
Why this rating
Based on the large cohort study design.
Source
Association of carbohydrate and saturated fat intake with cardiovascular disease and mortality in Australian women
Sarah Gribbin et al. · Heart · 2021
DOI 10.1136/heartjnl-2021-319654
cohort · n=9899Cited 20×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
More from this paper
- Higher carbohydrate intake was associated with lower CVD risk, with the lowest risk for quintile 3 (41.0%–44.3% energy as carbohydrate) versus quintile 1 (<37.1% energy as carbohydrate) (OR 0.56, 95% CI 0.35 to 0.91, p=0.02).Strong
- There was no significant association between carbohydrate intake and mortality (p trend =0.69).Strong
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