Research

Energy balance

Semaglutide has been shown to result in a loss of almost 12% of body weight over a 68-week period.

Semaglutide can be considered an effective option for significant weight loss in eligible patients.

StrongSupportsmedium confidence
Manufacturer-sponsored randomised controlled trials have shown a loss of almost 12% of body weight over a 68-week period.
Joel Lexchin et al. · Drug and Therapeutics Bulletin · 2023

Why this rating

Based on manufacturer-sponsored randomised controlled trials.

Source

Semaglutide: a new drug for the treatment of obesity

Joel Lexchin et al. · Drug and Therapeutics Bulletin · 2023

DOI 10.1136/dtb.2023.000007

otherCited 18×
Read the paper
DOI resolved against Crossref · corpus check 2026-06-10

This is one finding among thousands. Every one is graded and traced to its source, so you can see what the evidence actually supports. Browse the research →