Research
Metabolic adaptation
Alanine aminotransferase levels decreased with GLP-1RA and combination therapy.
Practitioners may consider monitoring liver enzyme levels when prescribing GLP-1RAs and combination therapy.
StrongSupportsmedium confidence
Alanine aminotransferase levels decreased with GLP‐1RA and combination therapy.
Why this rating
The study is based on a retrospective analysis of prospectively collected data.
Source
<scp>Glucagon‐like peptide</scp> ‐1 receptor agonists and <scp>sodium‐glucose cotransporter</scp> ‐2 inhibitors for the treatment of diabetes mellitus in liver transplant recipients
Katina Zheng et al. · Diabetes Obesity and Metabolism · 2024
DOI 10.1111/dom.15769
cohort · n=362Cited 13×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
More from this paper
- GLP-1 receptor agonists (GLP-1RAs) and combination therapy led to a significant decrease in mean glycated hemoglobin (HbA1c) levels by −3.5% at 12 months compared to DPP-4 inhibitors.Strong
- Both GLP-1RAs and combination therapy resulted in significant weight loss, with GLP-1RAs showing a mean weight loss of −5.2 kg at 12 months.Strong
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