Research
Hormonal
Only 5 mg once-weekly tirzepatide could induce significant alteration in LDL-C before sensitivity analysis.
Clinicians should note that the 5 mg dose of tirzepatide may be more effective for lowering LDL-C compared to higher doses.
StrongQualifiesmedium confidence
Only 5mg once-weekly tirzepatide (P < 0.05), not 10 or 15 mg, could induce significant alteration in LDL-C before sensitivity analysis.
Why this rating
Supported by a meta-analysis of randomized controlled trials.
Source
Effect of the Dual Glucose‐Dependent Insulinotropic Peptide/Gulcagon‐like Peptide 1 Receptor Agonist Tirzepatide on Lipid Profile and Waist Circumference: A Systematic Review and Meta‐analysis
Dan Yu et al. · Clinical Therapeutics · 2023
Meta-analysisCited 12×
Read the paper This is one finding among thousands. Every one is graded and traced to its source, so you can see what the evidence actually supports. Browse the research →