Research
Hormonal
Weight loss in both diet groups seems to have been driven by the reduction of glycemic load (GL) more so than dietary fat or calories.
Reducing glycemic load may be more effective for weight loss than focusing solely on fat or calorie reduction.
StrongSupportsmedium confidence
As predicted by the carbohydrate–insulin model of obesity, weight loss in both diet groups of DIETFITS seems to have been driven by the reduction of GL more so than dietary fat or calories.
Why this rating
Based on the large randomized controlled trial design.
Source
Evidence for the carbohydrate–insulin model in a reanalysis of the Diet Intervention Examining The Factors Interacting with Treatment Success (DIETFITS) trial
Adrián Soto-Mota et al. · American Journal of Clinical Nutrition · 2023
cohort · n=609Cited 10×
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