Research
Energy balance
Weight loss can be achieved with either a healthy low-carbohydrate diet (LCD) or a healthy low-fat diet (LFD).
Both LCD and LFD can be effective for weight loss in individuals with overweight or obesity.
StrongSupportsmedium confidence
The Diet Intervention Examining The Factors Interacting with Treatment Success (DIETFITS) trial demonstrated that meaningful weight loss can be achieved with either a 'healthy low-carbohydrate diet' (LCD) or 'healthy low-fat diet' (LFD).
Why this rating
Based on the large randomized controlled trial design.
Source
Evidence for the carbohydrate–insulin model in a reanalysis of the Diet Intervention Examining The Factors Interacting with Treatment Success (DIETFITS) trial
Adrián Soto-Mota et al. · American Journal of Clinical Nutrition · 2023
DOI 10.1016/j.ajcnut.2022.12.014
cohort · n=609Cited 10×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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