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By the fifth month, nearly one-half (46%) of semaglutide users had discontinued the treatment.
Practitioners should be aware of the high discontinuation rates when prescribing semaglutide.
StrongSupportsmedium confidence
By the fifth month, nearly one-half (46%) had discontinued the treatment.
Why this rating
Based on the large sample size of 15,811 participants.
Source
Titration and discontinuation of semaglutide for weight management in commercially insured US adults
Yunwen Xu et al. · Obesity · 2025
DOI 10.1002/oby.24315
cohort · n=15811Cited 8×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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